Between 1800 and 1840, the nation's most dramatic population expansion occurred:

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The period between 1800 and 1840 saw a significant population expansion in the western regions of the country, beyond the Appalachian Mountains. This can be attributed to factors such as the Louisiana Purchase of 1803, which opened up new territories for settlement, and the availability of cheap land and better economic opportunities in the West. The population growth in New England and Atlantic seaports was more gradual and not as significant during this period. The Deep South saw a population increase as well, but it was not as dramatic as that of the Western territories.

Between 1800 and 1840, the Nation's Most Dramatic Population Expansion