The amendment to the Constitution that barred the manufacture or sale of intoxicating liquors went into effect in:

Name: The amendment to the Constitution that barred the manufacture or sale of intoxicating liquors went into effect in:
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The amendment referred to is the 18th Amendment, also known as the Prohibition Amendment, which went into effect in 1920, making it illegal to manufacture, sell or transport intoxicating liquors within the United States.

The Amendment to the Constitution That Barred the Manufacture or Sale