Which of the following interactions causes a change from the R state (oxy form) to the T state (deoxy form) of hemoglobin?
A) interactions between heme groups
B) protonation of the R-group of His146 on the subunit to allow formation of a salt bridge with Lys40 on the subunit
C) salt bridge formed by 1-Arg141 to the carboxylate of 2Asp126
D) protonation of the 1 subunit terminal carboxyl group disrupts a salt bridge with 2Lys 127
E) none of the above
Correct Answer:
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