Which of the following shows the correct and complete flow of electrons for ribonucleotide reductase? A)NADH$\rarr$FAD $\rarr$thioredoxin $\rarr$ ribonucleotide reductase B)NADPH $\rarr$ glutathione $\rarr$ glutaredoxin $\rarr$ ribonucleotide reductase C)NADPH $\rarr$ thioredoxin $\rarr$cytochrome-b $\rarr$ ribonucleotide reductase D)FADH₂ $\rarr$glutathione $\rarr$ glutaredoxin $\rarr$ribonucleotide reductase E)none of the above

Question

Quizplus · Accepted Answer

Ribonucleotide reductase is activated by the reducing agents NADPH, which is converted to NADP+, and glutathione or glutaredoxin, which is converted to a disulfide form. These reducing agents donate electrons to ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides. Cytochrome-b and FAD are not involved in the reduction of ribonucleotide reductase. Thioredoxin can also act as a reducing agent for ribonucleotide reductase but is not necessary for its function. Choice A includes NADH and FAD, which are not involved in ribonucleotide reductase activation. Choice D includes additional molecules that are not needed for ribonucleotide reductase function. Thus, B is the best choice.

Which of the Following Shows the Correct and Complete Flow →\rarr→

Which of the Following Shows the Correct and Complete Flow $\rarr$