In antibody light chain production, combination of V and J regions occurs at the _____ level; combination of J and C regions occurs at the _____ level.

Question

Quizplus · Accepted Answer

V and J regions are combined at the DNA level through the process of V(D)J recombination, which occurs during B cell development in the bone marrow. However, the final combination of J and C regions occurs at the RNA level through splicing, which results in the mature messenger RNA (mRNA) for the light chain.

In Antibody Light Chain Production, Combination of V and J