What is the mechanism by which enhancers, despite the fact that they are often several kilobase pairs away from the promoter, activate transcription?
A)DNA unwinding
B)DNA looping
C)chromatin remodeling
D)DNA hairpin formation
E)none of the above

Question

Quizplus · Accepted Answer

Enhancers can activate transcription by looping the DNA to bring distal enhancer elements in close proximity to the promoter region, allowing for the transcription factors and RNA polymerase to interact and initiate transcription. This looping mechanism enables the enhancer elements to have an effect on the transcriptional activity of the promoter, despite their distance.

What Is the Mechanism by Which Enhancers, Despite the Fact