Which of the following describes the most stable conformation of trans-1-tert-butyl-3-methylcyclohexane?
A)Both groups are equatorial.
B)Both groups are axial.
C)The tert-butyl group is equatorial and the methyl group is axial.
D)The tert-butyl group is axial and the methyl group is equatorial.
E)none of the above

Question

Quizplus · Accepted Answer

The most stable conformation of a cyclohexane molecule has its larger groups in the equatorial positions to avoid steric hindrance with neighboring groups. In this case, the tert-butyl group is bulkier than the methyl group, therefore the tert-butyl group should be placed in the equatorial position while the methyl group occupies the axial position. This way, there is less steric strain between the groups compared to the other possible conformations.

Which of the Following Describes the Most Stable Conformation of Trans-1-Tert-Butyl-3-Methylcyclohexane