A decapeptide undergoes partial hydrolysis to give peptides whose amino acids are shown below.Reaction of the decapeptide with Edman's reagent releases PTH-leu.What is the sequence of the decapeptide? (1)Pro,Ser (5)Glu,Ser,Val,Pro
(2)Gly,Gly (6)Glu,Pro,Gly
(3)Met,Ala,Leu (7)Met,Leu
(4)Gly,Ala (8)His,Val

Question

Quizplus · Accepted Answer

From the partial hydrolysis, we can see that the decapeptide contains Leu, Met, Ala, Gly, Glu, Pro, and Ser.

The reaction with Edman's reagent releases PTH-leu, indicating that the first amino acid in the sequence is leucine.

From the given options, only option E has leucine as the first amino acid and contains all the amino acids identified from the partial hydrolysis. Therefore, the sequence of the decapeptide is Leu-Met-Ala-Gly-Gly-Glu-Pro-Ser-Val-His.

A Decapeptide Undergoes Partial Hydrolysis to Give Peptides Whose Amino