What detail in Ghirlandaio's Nativity and Adoration of the Shepherds references the new interest in Classical subjects?

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The architectural details surrounding Mary in Ghirlandaio's Nativity and Adoration of the Shepherds reference the new interest in Classical subjects, particularly the incorporation of Classical architecture in Renaissance art. The use of pilasters, arches, and a coffered ceiling are all elements of Classical architecture.

What Detail in Ghirlandaio's Nativity and Adoration of the Shepherds