Protein diseases can be caused by which of the following
A)mutations affecting the 1° structure.
B)mutations affecting the 3° structure.
C)changes in the post-synthetic processing of proteins.
D)All of the above are potential causes.
E)None of the above are potential causes.

Question

Quizplus · Accepted Answer

All of the listed options are potential causes of protein diseases. Mutations affecting the primary (1°) structure can alter the amino acid sequence, which can affect the folding and stability of the protein. Mutations affecting the tertiary (3°) structure can disrupt the overall shape and function of the protein. Changes in post-synthetic processing, such as incorrect folding, glycosylation or phosphorylation can affect the biological activity and stability of the protein. Therefore, all three factors can contribute to the development of protein diseases.

Protein Diseases Can Be Caused by Which of the Following