Examine the three sequences below for collagen-like proteins and their melting temperatures (Tm) .(Note: Flp = fluoroproline;Hyp = hydroxyproline) Based on this data,what is the most important feature in determining the strength of the collagen protein?
1) …-Pro-Hyp-Gly-Pro-Hyp-Gly-Pro-Hyp-Gly-… Tm=60oC
2) …-Pro-Flp-Gly-Pro-Flp-Gly-Pro-Flp-Gly-… Tm=78oC
3) …-Gly-Pro-Thr-Gly-Pro-Thr-Gly-Pro-Thr-… Tm=30oC
A) hydrogen bonding
B) inductive effect
C) electrostatic effect
D) electrostatic and Inductive effect are equal
E) hydrogen bonding and inductive effect are equal
Correct Answer:
Verified
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