A deficiency in the enzyme PEPCK (PEP carboxykinase)would
A)block function of the malate/aspartate shuttle.
B)block transfer of reducing equivalents across the membrane in the heart and liver.
C)inhibit formation of ATP via oxidative phosphorylation.
D)inhibit formation of NADH.
E)decrease flux through gluconeogenesis.

Question

Quizplus · Accepted Answer

PEPCK is an important enzyme involved in the gluconeogenesis pathway. A deficiency in PEPCK would decrease the flux through gluconeogenesis, leading to a decreased ability to produce glucose from non-carbohydrate precursors such as amino acids and fatty acids.

A Deficiency in the Enzyme PEPCK (PEP Carboxykinase)would