Serine proteases use _________ to catalyze the cleavage of a peptide bond.
(I)covalent catalysis
(II)proximity and orientation effects
(III)general base catalysis
(IV)electrostatic catalysis

Question

Quizplus · Accepted Answer

Serine proteases utilize a combination of mechanisms to catalyze the cleavage of peptide bonds, including covalent catalysis, proximity and orientation effects, general base catalysis, and electrostatic catalysis. These mechanisms work together to stabilize the transition state and lower the activation energy for the reaction.

Serine Proteases Use _________ to Catalyze the Cleavage of a Peptide