Which of the Following Metabolic Conversions Is Considered to Be $\to$

Which of the following metabolic conversions is considered to be the major control point of glycolysis?

A) fructose-1,6-bisphosphate $\to$ dihydroxyacetone phosphate + glyceraldehyde-3-phosphate
B) glucose $\to$ glucose-6-phosphate
C) 2-phosphoglyerate $\to$ phosphoenolpyruvate
D) fructose-6-phosphate $\to$ fructose-1,6-bisphosphate
E) phosphoenolpyruvate $\to$ pyruvate