In A-DNA
A)the glycosidic bond is in the syn conformation with a C3'-endo sugar pucker.
B)the glycosidic bond is in the syn conformation with a C2'-endo sugar pucker.
C)the glycosidic bond is in the anti conformation with a C3'-endo sugar pucker.
D)the glycosidic bond is in the anti conformation with a C2'-endo sugar pucker.
E)the glycosidic bond conformation and sugar pucker is dependent on the base.

Question

Quizplus · Accepted Answer

In A-DNA, the glycosidic bond is in the anti conformation with a C3'-endo sugar pucker. This conformation is favored by the A-form helix, which has a wider and shallower major groove compared to the B-form helix. This conformation also allows for better stacking of the bases in the helix.