What is abortive initiation of transcription by RNA polymerase?
A)initiation at nonpromoter sites prior to dissociation of the polymerase.
B)synthesis of short transcripts about 10 nucleotides long prior to commitment to elongation.
C)pausing by the polymerase during elongation.
D)failure to undergo the closed to open transition in the pre-initiation complex.
E)none of the above

Question

Quizplus · Accepted Answer

Abortive initiation of transcription involves the synthesis of short transcripts (about 10 nucleotides long) by RNA polymerase before committing to elongation. These short transcripts are synthesized and released repeatedly until the polymerase undergoes a transition from closed to open complex, thereby allowing for elongation to proceed.

What Is Abortive Initiation of Transcription by RNA Polymerase