The thermodynamic requirement for proofreading is met by
A)aminoacyl-tRNA binding to the ribosomal A site.
B)hydrolysis of GTP by EF-Tu
C)transpeptidation mediated by IF-2.
D)transpeptidation mediated by RF-3
E)none of the above.

Question

Quizplus · Accepted Answer

Hydrolysis of GTP by EF-Tu during the delivery of aminoacyl-tRNA to the ribosome can provide the thermodynamic energy required for proofreading. This allows incorrect tRNA molecules to be rejected before peptide bond formation occurs.

The Thermodynamic Requirement for Proofreading Is Met by