How does the transcriptional machinery gain access to the nucleosome-sequestered DNA?
(I) Methylation of DNA prevents histone binding.
(II) Chromatin-remodeling complexes allow sections of DNA to be transiently exposed to transcription factors.
(III) The transcription proteins have higher affinity for DNA and push the histones away from binding sites.
A) I,II,III
B) I,II
C) II,III
D) I,III
E) II only
Correct Answer:
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