Upstream transcription factors typically contain the following domain(s)
(I)a DNA binding domain.
(II)an activation domain,which often is rich in negative charges.
(III)an ATP binding domain,which is used to promote conformational change in the DNA.
A)I,II
B)I,II,III
C)I,III
D)II,III
E)none of the above

Question

Quizplus · Accepted Answer

Upstream transcription factors typically contain a DNA binding domain to bind to specific sequences in the promoter region of a gene and an activation domain, which can be rich in negative charges, to recruit other proteins necessary for transcription. They do not typically contain an ATP binding domain, so option III is incorrect. Therefore, the correct answer is choice A, which includes both the DNA binding and activation domains.

Upstream Transcription Factors Typically Contain the Following Domain(s)