The most consistent brain structure abnormality that researchers have found in people with schizophrenia is enlargement of the:

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Enlargement of the ventricles (fluid-filled spaces in the brain) is the most consistent brain structure abnormality found in people with schizophrenia. This suggests that there may be decreased brain tissue volume and neural connectivity in individuals with schizophrenia. Enlargement of the frontal lobe and left temporal lobe are less consistent findings, and abnormalities in the brain stem are not typically associated with schizophrenia.

The Most Consistent Brain Structure Abnormality That Researchers Have Found