In response to a stressor, the pituitary gland triggers ACTH release, which causes the adrenal medulla to release stress hormones called catecholamines.

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The pituitary gland triggers the release of ACTH which causes the adrenal cortex (not medulla) to release stress hormones called glucocorticoids, such as cortisol. The adrenal medulla does release catecholamines such as adrenaline and noradrenaline in response to stress.

In Response to a Stressor, the Pituitary Gland Triggers ACTH