Two 4-year-olds (Charlie and Lisa) have mucopolysaccharidosis I (MPSI) .Charlie has severe dysmorphic features and many skeletal anomalies.Lisa has only mildly coarse features and slight developmental delay.What is the best explanation for these differences?
A) Skewed X inactivation allowed more paternal X expression for Lisa and more maternal X expression for Charlie.
B) Lisa's mother had better prenatal care,including good diet,exercise,and vitamins than Charlie's mother.
C) It is likely that Lisa has been misdiagnosed and really has MPSII.
D) The disorder has wide variability in expression of severity.
Correct Answer:
Verified
Q9: Why does a newborn with a genetic
Q13: A woman who is a carrier for
Q14: Why is it important to diagnose type
Q15: What is the expected outcome of pregnancy
Q16: How are the two mucopolysaccharide disorders Hurler
Q17: Which enzyme is deficient in individuals with
Q21: A son with osteogenesis imperfecta is born
Q25: Which clinical manifestation in a 6-month-old infant
Q26: Which manifestation is most common among individuals
Q27: What is the most common cause of
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents