In myasthenia gravis, which two pulmonary function values are the most sensitive in detecting respiratory muscle weakness?
1) TLC and VC
2) PImax and PEmax
3) VC and expired volume per unit time (V_E)
4) VC and tidal volume (V_T)

Question

Quizplus · Accepted Answer

The most sensitive pulmonary function values to detect respiratory muscle weakness in myasthenia gravis are PImax and PEmax, which assess the maximum inspiratory and expiratory muscle strength, respectively, and VC, which evaluates the maximal volume of air that can be forcefully exhaled after maximal inhalation. TLC (total lung capacity) is not as useful in detecting respiratory muscle weakness as it reflects the total amount of air that the lungs can hold. The other options, expired volume per unit time and tidal volume, are not specific for detecting respiratory muscle weakness.

In Myasthenia Gravis, Which Two Pulmonary Function Values Are the Most