A 45-year-old man has a history of heart failure and is diagnosed with pulmonary arterial hypertension. Initially, he is prescribed treprostinil (Tyvaso) 3 breathes (18 mcg) per treatment session via the Tyvaso Inhalation System. Upon first administration, the patient feels nauseated, throat irritation, muscle pain, and experiences flushing. What is the best next course of action?

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Quizplus · Accepted Answer

The initial dose for Tyvaso is 3 breathes (18 mcg) per treatment session. If not tolerated, the dose may be reduced to 1 to 2 breathes per session and then increased to 3. Tyvaso should be increased by 3 breathes every 1 to 2 weeks until 9 breathes (54 mcg) per treatment session is reached.

A 45-Year-Old Man Has a History of Heart Failure and Is