Elimination of norepinephrine at the synaptic cleft is accomplished by which of the following mechanisms?
I)Reuptake
II)Metabolization by AChE
III)Metabolization by MAO
IV)Metabolization by COMT

Question

Elimination of norepinephrine at the synaptic cleft is accomplished by which of the following mechanisms?
 I)Reuptake
II)Metabolization by AChE
III)Metabolization by MAO
IV)Metabolization by COMT

Quizplus · Accepted Answer

Elimination of norepinephrine at the synaptic cleft is primarily accomplished by reuptake into the presynaptic neuron, but it can also be metabolized by the enzymes MAO and COMT. AChE, on the other hand, is responsible for metabolizing acetylcholine, not norepinephrine. Therefore, the correct choices are I, III, and IV, making option D the best choice.

Elimination of Norepinephrine at the Synaptic Cleft Is Accomplished by Which