What is believed to be the underlying cause of prion protein plaque formation?
A) The PrPSc proteins are misfolded and aggregated from PrPc proteins.
B) The unstructured N-terminal region of PrPc is thought to remain unfolded.
C) The normal PrPc proteins are aggregated.
D) The PrPSc protein adheres to and inhibits cell membranes.
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