The result of TRADD proteins binding to TNF receptors is that
A) TRADD is phosphorylated.
B) an activated adaptor complex is formed.
C) downstream signaling proteins are inactivated.
D) TNF is degraded.

Question

Quizplus · Accepted Answer

TRADD proteins binding to TNF receptors leads to the formation of an activated adaptor complex which initiates downstream signaling pathways. This ultimately leads to cellular responses such as inflammation, cell death, and immune system activation. TRADD may also become phosphorylated in this process, but this is not the main result of its binding to TNF receptors. The binding of TRADD proteins to TNF receptors does not result in the inactivation of downstream signaling proteins or the degradation of TNF.

The Result of TRADD Proteins Binding to TNF Receptors Is