Which of the following is the cause of the irreversible blockage of the catalytic activity of lipoamide-containing enzymes?
A) cheilosis
B) pellagra
C) beriberi
D) arsenic poisoning

Question

Quizplus · Accepted Answer

Arsenic poisoning is known to irreversibly block the catalytic activity of lipoamide-containing enzymes by reacting with the essential sulfhydryl group (-SH) on lipoic acid, leading to the formation of a stable arsenic-sulfur bond. This can lead to a buildup of toxic metabolites and cause severe health problems. Cheilosis, pellagra, and beriberi are all caused by deficiencies in certain vitamins and nutrients and do not directly affect lipoamide-containing enzymes.

Which of the Following Is the Cause of the Irreversible