How many ATPs are obtained from one acetyl-CoA run once through the TCA cycle,assuming that all resulting NADH and FADH₂ is used by the electron transport chain and oxidative phosphorylation to make ATP? A) 6.5 B) 9 C) 10 D) 11

Question

Quizplus · Accepted Answer

One acetyl-CoA run through the TCA cycle produces 3 NADH, 1 FADH2, and 1 GTP. Each NADH produces 2.5 ATP and each FADH2 produces 1.5 ATP in the electron transport chain and oxidative phosphorylation. The GTP can be converted to ATP. Therefore, the total ATP produced from one acetyl-CoA in the TCA cycle is: 
3 NADH x 2.5 ATP/NADH = 7.5 ATP 
1 FADH2 x 1.5 ATP/FADH2 = 1.5 ATP 
1 GTP = 1 ATP 
Total ATP = 7.5 + 1.5 + 1 = 10 ATP.

How Many ATPs Are Obtained from One Acetyl-CoA Run Once