The hormone insulin activates phosphofructokinase 2 (2PFK2).This leads to a(n)__________ in concentration of fructose 2,6 bisphosphate,which favors the __________ pathway.

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Activation of PFK2 by insulin leads to an increase in the concentration of fructose 2,6 bisphosphate, which is a potent activator of phosphofructokinase-1 (PFK1), the enzyme that catalyzes the rate-limiting step of glycolysis. This activation of glycolysis leads to an increase in glucose utilization and energy production, which is beneficial for the body during times of high energy demand or after a meal. Therefore, an increase in concentration of fructose 2,6 bisphosphate favors the glycolysis pathway.

The Hormone Insulin Activates Phosphofructokinase 2 (2PFK2)