Which hormone slows down glycolysis while stimulating gluconeogenesis through the phosphorylation of phosphofructokinase 2 (PFK2)and fructose-2,6-bisphosphatase?

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Glucagon, known as the "starvation hormone," is released from the pancreas when blood glucose levels are low. Glucagon activates a signaling cascade that leads to the phosphorylation and inactivation of PFK2 and the activation of fructose-2,6-bisphosphatase, resulting in a decrease in glycolysis and an increase in gluconeogenesis. This allows the body to produce glucose when it is needed, such as during fasting or periods of low blood sugar. Insulin, on the other hand, promotes glycolysis by stimulating PFK2 and inhibiting fructose-2,6-bisphosphatase. ATP is not a hormone, and protein kinase is a general term for enzymes that phosphorylate proteins and can be activated by a variety of signals.

Which Hormone Slows Down Glycolysis While Stimulating Gluconeogenesis Through the Phosphorylation