Which pair of opposite enzymes in the glycolysis and gluconeogenesis pathway are not allosterically regulated but rather regulated by compartmentalization?

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Hexokinase and glucose-6-phosphatase are not allosterically regulated but are regulated by compartmentalization. Hexokinase is located in the cytoplasm and has a low Km for glucose, whereas glucose-6-phosphatase is located in the endoplasmic reticulum of liver and kidney cells and has a high Km for glucose. This difference in localization and Km values allows for the regulation of the flow of glucose into and out of these cells based on the metabolic needs of the organism.

Which Pair of Opposite Enzymes in the Glycolysis and Gluconeogenesis