The biosynthesis of triacylglycerols in animals uses which citrate cycle intermediate in the liver?
A) malate
B) acetyl-CoA
C) isocitrate
D) succinate

Question

Quizplus · Accepted Answer

The biosynthesis of triacylglycerols in animals uses acetyl-CoA, which is a key intermediate of the citrate cycle, in the liver. Acetyl-CoA condenses with glycerol 3-phosphate to form phosphatidic acid, which is the precursor of triacylglycerols. Malate and succinate are intermediate metabolites of the citrate cycle but not directly involved in triacylglycerol biosynthesis. Isocitrate is oxidized to α-ketoglutarate in the citrate cycle.

The Biosynthesis of Triacylglycerols in Animals Uses Which Citrate Cycle