Compared with the COX-2 enzyme,COX-1 has
A) a larger active site.
B) a smaller active site.
C) a more elongated three-dimensional structure.
D) more -barrels.

Question

Compared with the COX-2 enzyme,COX-1 has
A) a larger active site. 
B) a smaller active site. 
C) a more elongated three-dimensional structure. 
D) more -barrels.

Quizplus · Accepted Answer

COX-1 has a smaller active site compared to COX-2. This is because COX-1 has a more narrow substrate binding pocket that accommodates smaller molecules like arachidonic acid, while COX-2 has a larger pocket that can bind larger molecules like certain anti-inflammatory drugs.

Compared with the COX-2 Enzyme,COX-1 Has