A compound is added to a cell and dihydrofolate reductase activity is reduced.If this compound is __________,it can be predicted that a similar result would be seen if __________ were added instead.
A) methotrexate; aminopterin
B) methotrexate; raltitrexed
C) aminopterin; raltitrexed
D) aminopterin; fluorodeoxyuridine- -monophosphate

Question

A compound is added to a cell and dihydrofolate reductase activity is reduced.If this compound is __________,it can be predicted that a similar result would be seen if __________ were added instead.
A) methotrexate; aminopterin 
B) methotrexate; raltitrexed 
C) aminopterin; raltitrexed 
D) aminopterin; fluorodeoxyuridine- -monophosphate

Quizplus · Accepted Answer

Methotrexate and aminopterin are both inhibitors of dihydrofolate reductase, so if one reduces its activity, the other is likely to do so as well. Raltitrexed is not a dihydrofolate reductase inhibitor and fluorodeoxyuridine-monophosphate targets thymidylate synthase, so neither of these compounds would be predicted to have the same effect on dihydrofolate reductase activity.

A Compound Is Added to a Cell and Dihydrofolate Reductase