Analysis of phosphorylated proteins in a cell with a fully active AMPK would reveal that __________ is phosphorylated.
A) cytochrome oxidase
B) cytochrome c
C) phosphofructokinase-2
D) PPAR

Question

Analysis of phosphorylated proteins in a cell with a fully active AMPK would reveal that __________ is phosphorylated.
A) cytochrome oxidase 
B) cytochrome c 
C) phosphofructokinase-2 
D) PPAR

Quizplus · Accepted Answer

AMPK phosphorylates and thereby inhibits phosphofructokinase-2, an enzyme involved in glycolysis. This leads to a decrease in glycolysis and an increase in alternative pathways such as fatty acid oxidation, which is promoted by AMPK activation. Therefore, if a cell has fully active AMPK, the phosphorylation of phosphofructokinase-2 should be observed. The other options are not directly related to the function of AMPK.

Analysis of Phosphorylated Proteins in a Cell with a Fully