Which antibiotic functions by inhibiting DNA gyrase?
A) vancomycin
B) coumermycin
C) aminoglycosides
D) clindamycin

Question

Quizplus · Accepted Answer

Coumermycin is the only antibiotic on the list that functions by inhibiting DNA gyrase, a type II topoisomerase enzyme that is essential for DNA replication and transcription in bacteria. Vancomycin targets cell wall synthesis, aminoglycosides interfere with protein synthesis, and clindamycin inhibits protein synthesis by binding to the 50S subunit of bacterial ribosomes.

Which Antibiotic Functions by Inhibiting DNA Gyrase