What therapy has been shown to reduce sputum viscosity in the number of exacerbations in patients with cystic fibrosis?

Question

Quizplus · Accepted Answer

Use of DNase (dornase alfa) has been shown to reduce sputum viscosity and improve clearance of airway secretions in patients with cystic fibrosis. It has also been found to decrease the number of exacerbations and improve lung function. Mucomyst (acetylcysteine) is also a mucolytic agent but has not been found to be as effective as DNase. Aerosolized saline can help with airway clearance but does not directly reduce sputum viscosity. Bronchoscopy may be used to clear retained mucus but is invasive and not a first-line therapy for routine airway clearance in cystic fibrosis.

What Therapy Has Been Shown to Reduce Sputum Viscosity in the Number