If the international normalized ratio (INR) result is above the therapeutic range in a patient with atrial fibrillation on warfarin, what might the clinician do?

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Quizplus · Accepted Answer

If the INR result is above the therapeutic range, withholding one or more days of anticoagulant therapy is usually the initial management approach to reduce the INR to the desired level. Restarting therapy at a lower dose immediately is not recommended as it may cause an increased risk of thrombotic events. Stopping the warfarin for a week is not necessary unless the patient is at risk of bleeding. The prothrombin time and INR should be reevaluated within 1-2 weeks after any dosage adjustments or changes in therapy.

If the International Normalized Ratio (INR) Result Is Above the Therapeutic