The blocking of translation of an mRNA by miRNA occurs because the miRNAــــــــــــــــــــــ .
A)binds to the 3'-UTR of the mRNA and prevents translation
B)targets the mRNA for degradation by Slicer
C)binds to the 5'-UTR to prevent the ribosome from binding
D)folds into alternative stem-loop structure and protects the mRNA from nuclease cleavage

Question

Quizplus · Accepted Answer

miRNA binds to the 3'-UTR of the mRNA and forms an RNA-induced silencing complex (RISC) that prevents translation. This occurs through a combination of blocking ribosome binding and promoting deadenylation of the mRNA, which ultimately leads to degradation by exonucleases.

The Blocking of Translation of an MRNA by MiRNA Occurs