A 30-year-old man presents to the physician with a painless ulcer on his penis.An RPR performed on the man is reactive 1:128,and the MHA-TP test is positive.This man has:

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The presentation of a painless ulcer on the penis is consistent with syphilis, specifically primary syphilis. The reactive RPR and positive MHA-TP test confirm the diagnosis of Treponema pallidum infection. Neisseria gonorrhoeae and Chlamydia trachomatis can cause urethritis but usually present with discharge and not a painless ulcer. Mycoplasma hominis is not typically associated with genital ulceration.

A 30-Year-Old Man Presents to the Physician with a Painless