A 25- year-old female is in kidney failure and needs a transplant.She is A positive and HLA A1A3/B5B7/C2C9/DR4DR8.Which of the following donors would be the best match?

Question

Quizplus · Accepted Answer

The best match is the donor who has the most matching HLA antigens with the recipient. In this case, the sister (donor B) is the best match as she shares the A and B HLA antigens with the recipient, whereas the other potential donors do not share as many matching HLA antigens. Donor A has matching A and C antigens but has different B and DR antigens. Donor C has matching B and DR antigens but has different A and C antigens. Donor D has different A, B, C, and DR antigens.

A 25- Year-Old Female Is in Kidney Failure and Needs