A patient with hereditary angioedema will present with swelling in the tissues and has which of the following deficiencies?

Question

Quizplus · Accepted Answer

Hereditary angioedema is caused by a deficiency or dysfunction of C1 inhibitor, which leads to excessive activation of the complement and bradykinin pathways. This results in recurrent episodes of localized swelling in the tissues. Deficiencies in C5,C6,C7,C8 are associated with increased susceptibility to Neisseria infections but do not cause hereditary angioedema. Phagocytic cell function and mature B cells are not directly related to hereditary angioedema.

A Patient with Hereditary Angioedema Will Present with Swelling in the Tissues