A 40-year-old female patient has increased TSH and decreased rT3 and T4 levels with a normal T3 level.Antithyroglobulin is measured as 1:1280,and the antimicrosomal level is reportedly 1:6400.This patient most likely has:

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The increased TSH and decreased T4 levels with a normal T3 level indicate hypothyroidism. The high levels of antithyroglobulin and antimicrosomal antibodies suggest Hashimoto's thyroiditis, which is a common cause of hypothyroidism. Neither type 1 diabetes nor systemic lupus erythematosus is typically associated with thyroid dysfunction. Graves' disease, on the other hand, is a cause of hyperthyroidism, not hypothyroidism, and would not be expected to have the same pattern of laboratory values seen in this patient.

A 40-Year-Old Female Patient Has Increased TSH and Decreased RT3