A 16-year-old male goes to his physician for an annual checkup.A routine urinalysis indicates the presence of blood,an increase in protein,and an increase in urea.The young man reports that he has been feeling tired and has a persistent cough.The doctor orders additional lab testing,including a serum test for rheumatoid factor,antinuclear antibody testing,anti-streptolysin O testing,and testing for the presence of anti-basement membrane antibodies.Only the latter test was positive.What is the most likely cause of the symptoms?

Question

Quizplus · Accepted Answer

The presence of blood, an increase in protein, and an increase in urea in the urinalysis, along with symptoms of fatigue and a persistent cough, suggest a possible kidney disorder. The positive anti-basement membrane antibody test points towards Goodpasture's syndrome, a rare autoimmune disorder that can cause both kidney and lung damage. Lupus, multiple sclerosis, and rheumatoid arthritis are not typically associated with kidney and lung involvement as seen in Goodpasture's syndrome.

A 16-Year-Old Male Goes to His Physician for an Annual