As measured in flow cytometry,cells that are the smallest and have the least granules would be identified as:

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Lymphocytes are the smallest of the white blood cells and have the least amount of granules. This makes them easily distinguishable by flow cytometry. Granulocytes, on the other hand, have abundant granules and are much larger than lymphocytes. Monocytes are larger than lymphocytes but smaller than granulocytes and have variable amounts of granules. Erythrocytes are not nucleated and are not typically analyzed by flow cytometry.

As Measured in Flow Cytometry,cells That Are the Smallest and Have