Which immunoglobulin activates the classical complement pathway?

Name: Which immunoglobulin activates the classical complement pathway?
Brand: Quizplus
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Question

Quizplus · Accepted Answer

IgM is the only immunoglobulin that can activate the classical complement pathway because of its pentameric structure and multiple antigen-binding sites. When IgM complexes with an antigen, it can bind and activate the complement component C1q, leading to the recruitment and activation of downstream complement components.

Which Immunoglobulin Activates the Classical Complement Pathway