The most significant finding that suggests a diagnosis of delirium is

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Rapid onset of symptoms that differ from baseline functioning is a key characteristic of delirium. This differentiates it from dementia, which has a slow, progressive onset of symptoms. Difficulty in finding the right word to express an idea may be a symptom of cognitive impairment, but it is not specific to delirium. Delusions of grandiosity are more commonly associated with mania or other psychotic disorders.

The Most Significant Finding That Suggests a Diagnosis of Delirium