Comparative genome hybridization detects which type of genetic abnormalities?

Question

Quizplus · Accepted Answer

Comparative genome hybridization (CGH) is a technique used to detect copy number variations (CNVs) in DNA samples. CNVs refer to the loss or gain of genetic material in comparison to a reference DNA sample. Therefore, CGH can detect amplifications (or deletions) relative to the reference DNA, making choice A the correct answer. Absolute gene numbers, inversions, and amino acid substitutions cannot be detected through CGH analysis.

Comparative Genome Hybridization Detects Which Type of Genetic Abnormalities