Thalassemias arise from changes in what part of the beta-globin gene?

Question

Quizplus · Accepted Answer

Thalassemias arise from changes in the splice recognition site of the beta-globin gene. This can result in abnormal splicing of the mRNA, which affects the production of hemoglobin and leads to anemia. Changes in other regions of the gene, such as the untranslated region or the ribosome binding site, may also affect gene expression but do not typically lead to thalassemia. The polyA tail is involved in mRNA stability and does not directly affect the production of hemoglobin.

Thalassemias Arise from Changes in What Part of the Beta-Globin